SeSDERMA Laboratories, an international cosmeceuticals company, recently introduced a new product for the non-injectable filler market at the October meeting of the International Congress of Aesthetics. FillDerma™ is a two-part treatment system which smoothes wrinkles using a combination of oil-based microspheres to penetrate and expand under the skin when hydrated, and an activator gel which contains matrixyl, a component popularly used as a collagen stimulator. FillDerma can be used alone or as a complement to Botox®, collagen, and other injectables.

Dr. Gabriel Serrano, founder of SeSDERMA Laboratories, worked with Dr. Gerard Robert of Lyon, France, to develop FillDerma. SeSDERMA Laboratories was the first European laboratory to introduce products containing glycolic acid and other
alphahydroxy acids and now has more than 150 products in the line which are sold only through physicians.

For more information on SeSDERMA Laboratories or the FillDerma product line, contact Raimundo Sala, Director of North
American Sales for SeSDERMA USA, at raimundo@sesdermausa.com.

SeSDERMA USA
404.846.2044
www.sesdermausa.com

Valeant Pharmaceuticals (NYSE: VRX), Costa Mesa, CA, has announced two additional line extensions for the Kinerase® brand,
Kinerase Gentle Daily Cleanser and Kinerase C6 Peptide Intensive Treatment, and has signed an agreement with Caleel+Hayden to co-promote the brand in high-end spas, a previously untapped market for Kinerase. In addition to its
Kinerase Cream and Lotion, Valeant launched Kinerase Intensive Eye Cream and Kinerase with SPF 15 earlier this year.
Valeant has also stepped up promotional activities surrounding the product line, has launched the product in a number of countries in Europe, and has plans to launch in a number of other countries in coming months.

“We announced earlier this year that we are building the Kinerase franchise into a global product line by launching a series of line extensions, expanding into new markets and increasing promotional activities around the brand,� President and Chief Operating Officer, Timothy C. Tyson said. “With the addition of the Gentle Daily Cleanser and the C6 Peptide Intensive Treatment, we have now launched four line extensions for the Kinerase brand this year and we have a number of other product
initiatives in the pipeline, including the introduction of Kinerase into the high-end spa market. These successful initiatives have allowed us to achieve 40 percent growth at the first half of 2004 for the Kinerase brand and we expect that growth to
accelerate. Building out the Kinerase brand is an important contributor to our growth strategy and these recent activities are further evidence of our commitment to consistent execution of our plans.�

Valeant Parmaceuticals
714.545.0100
www.valeant.com

Pacific Bioscience Laboratories, Inc., Philadelphia, PA, the Creators of the Sonicare® Toothbrush, bring the benefits of Sonic Oscillation Technology to skincare by unveiling the new CLARISONIC™ Skin Care Brush, the first sonic technology skincare product featuring a proprietary dual action oscillating brush system. CLARISONIC deeply cleanses and clarifies the skin and
can conveniently be incorporated into existing office procedures. In-practice and at-home, it provides gentle pre-treatment cleansing, daily skin health maintenance, and potentially enhances therapeutic response. The brush was introduced to more than 3,000 plastic surgeons, dermatologists, nurses, and other skincare professionals at Plastic Surgery 2004, held in Philadelphia in October.

The CLARISONIC Skin Care Brush gently and effectively cleans the skin better than manual cleansing. The brush oscillating motion works with the skin, not against it, by flexing the pores to effectively deep clean the skin. “Sonic technology offers a new method for skin cleansing. This allows for improved hygiene and smoothness in a manner which is gentle to the skin,� said Zoe D. Draelos, M.D., of Dermatology Consulting Services in Highpoint, NC. The sonic technology of the CLARISONIC works synergistically with the natural elasticity of the skin to provide gentle daily cleansing as part of a total skincare routine.

Pacific Bioscience Laboratories
888.525.2747
www.clarisonic.com

The Noix de Grenoble walnut trees in France are over 400 years old and widely admired for their longevity. Now, scientists have harvested their secret: it’s called Gatuline.

Researchers who comb the world looking for breakthrough ingredients, especially exotic ones, finally took a look at the Grenoble
trees. They discovered its potential to counteract the aging process, which led to the development of Gatuline7 Age Defense, a patented, pro-active anti-aging material that works on a number of levels.

[more]

Thermage, Inc., Hayward, CA, reports that in the past nine months since the Company introduced new treatment guidelines for its popular radiofrequency skin tightening and contouring procedure, predictability of efficacy and patient satisfaction have risen dramatically while boosting its already impressive safety record and greatly reducing the pain of treatment. The findings were presented by leading plastic surgeon Charles Hughes III, M.D., F.A.C.S., at the American Society for Plastic Surgery Annual Meeting from October 9-12, 2004, in Philadelphia, PA. Speaking to colleagues, the Director of the Indianapolis Institute for Plastic Surgery shared his most recent research showing that Thermage’s new multiple-pass treatment algorithm using moderate treatment settings, combined with the use of its advanced “fast� treatment tip technology, improved both the degree and predictability of results, increased overall patient comfort, and further reduced the rare risk of idiosyncratic side effects.

[more]

IntegreMed Holdings, Inc.’s consumer brand division, INTEGRIS, unveiled its latest in New Age Skincare systems at this year’s PATHWAYS to Beauty and Well-Being Conference in New York City. IntegreMed’s skincare products have long been used by
physicians and estheticians in a clinic or spa setting as a complete skincare regimen. These products have now been formulated for the consumer as a safe, at-home, noninvasive alternative to Botox®.

Integris’ flagship product is the BotoDerm™ System Kit, a four-step regimen designed to smooth, lift, tighten, resurface and replenish the skin to a rejuvenated state. Perfect for the face, neck and décolleté; in minutes, the BotoDerm System kit reveals radiant, younger looking skin. The BotoDerm System is a unique new age skincare product system for convenient home use. It provides a safe, at-home, non-toxic, non-invasive alternative to Botox, hence, NO APPOINTMENT
NECESSARY. BOTOX is a registered trademark of Allergan.

Integris, LLC
877.733.7627
www.integrisskincare.com

On a daily basis most of us wonder more about our bodily intake of vitamin C, rather than our topical application of the powerful
antioxidant known for its free radical fighting actions. So just in case you forget that extra serving of fruit or vegetables, Institut’ DERMed introduces Vital C Serum corrective treatments designed to protect skin from sun damage and prevent premature aging, a perfect suggestion to your spa clients who crave the very best for their skin!

Vital C Serum, designed for oily skin types, is a potent serum formulated with a high concentration of L-ascorbic acid, grape seed extracts and anti-oxidants to prevent immune cell suppression from UV light exposure. It protects the skin from sun damage and supports skin firmness. Vital C Serum should be applied to cleansed skin in the morning or evening, prior to moisturizing.

Institut’ DERMed
866.I.DERMED (433-7633)
www.idermed.com

For those who care deeply about your skin, trust your face to Institut’ DERMed, a serious skin care product. We all need protection from the elements, no matter what area of the country we call home. Clothes and SPF protect our bodies; a delicate formula is needed to protect something as gentle as your face. Institut’ DERMed presents Anti-Oxidant Rich Cream, a rich moisturizing cream formulated to hydrate and nourish the skin.

Anti-Oxidant Rich Cream contains active ingredient Black Tundra Moss Extract, a potent anti-oxidant known to protect skin against damaging free radical reactions which occur from exposure to environmental sunlight. Anti-Oxidant Rich Cream also lubricates and protects the skin from harsh winter weather conditions. Its nourishing antioxidants protect cellular DNA to prevent abnormal cell development as skin ages. Anti- Oxidant Rich Cream is suited for dehydrated, aging, and normal to
dry skin types. Add this product to your shelves for all seasons.

Institut’ DERMed
866.I.DERMED (433-7633)
www.idermed.com

DUSA Pharmaceuticals, Inc. (NASDAQ NMS:DUSA) announced the signing of a clinical trial agreement with the National Cancer
Institute (NCI) Division of Cancer Prevention (DCP) for the clinical development of Levulan® photodynamic therapy (PDT) for the treatment of high-grade dysplasia (HGD) within Barrett’s Esophagus (BE). DUSA and the NCI DCP will be working together to prepare an overall clinical development plan for Levulan PDT in this indication, starting with a Phase II trial and continuing through Phase III studies if appropriate.

[more]

Cynergy Products LLC, Buffalo, NY, introduces a new, practical method of application for physicianstrength glycolic peels. Gly+â„¢ individually wrapped pads are a sanitary way to prevent drying out and solution spills.

Generously sized at 9�x 7�, the pads are ideal for use on the face and other problem areas. GLY+ pads contain un-buffered glycolic solutions in strengths of 30%, 40%, 50%, 60%, and 70%. Gly+ peels are effective for the treatment of keratosis pilaris, actinic keratosis, hyperpigmentation, acne, fine lines and wrinkles, and sun damage. For best results, use in combination with other products in Cynergy’s GLY+ line.

Cynergy Products LLC
888.311.6881
www.cynergyinc.com